PURE Innovation Biotech
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Drug Discovery

Advancing hits to quality leads through parallel assays, medicinal chemistry, and data‑driven design.

Drug Discovery

Overview

We combine automation, computational design, and rigorous documentation to shorten research cycles and increase reproducibility.

Quality

GxP‑aligned methods and change control ready for scale.

Security

Project data isolated with audited access.

Capabilities

Target ID & Validation

Multi‑omics mining, CRISPR screens, orthogonal validation.

Assay Development

Biochemical, biophysical, and cell‑based assays with QC controls.

Hit Finding

HTS, DEL partners, and structure‑enabled virtual screens.

Lead Optimization

SAR cycles with AI‑assisted MMP & property prediction.

DMPK/ADME

In vitro panels for metabolic stability, permeability, CYP.

In‑vitro Efficacy

Mechanism‑of‑action studies and biomarker strategy.

Workflow

Define Target & Biology
Indications, biology package, and TPP alignment.
Assay & HTS Readiness
Robust assays, Z' validation, automation scripts.
Hit Triage
PAINS filtering, orthogonal reconfirmation, novelty checks.
Lead Series
Synthesis plan, potency/selectivity, in‑silico design loops.
ADME/Tox
Early risk flags, microsomes, PPB, hERG.
Candidate Selection
Data pack for preclinical nomination.

Platforms & Equipment

Liquid Handling

Automated pipetting and plate readers for throughput.

Biophysics

SPR/DSF/ITC partners; native MS via collaborators.

Informatics

Compound & data tracking, reproducible analytics.

Contact

Get in touch

We’d love to hear about your program.

Email: pibbiotech@gmail.com
HQ: Flat 701, 11 Florinis Street, 7th Floor, 1065 Nicosia, Cyprus

Collaborations

Partner with us for discovery, diagnostics, or manufacturing.

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